منابع مشابه
Glucocorticoids, epigenetic control and stress resilience
Glucocorticoid hormones play a pivotal role in the response to stressful challenges. The surge in glucocorticoid hormone secretion after stress needs to be tightly controlled with characteristics like peak height, curvature and duration depending on the nature and severity of the challenge. This is important as chronic hyper- or hypo-responses are detrimental to health due to increasing the ris...
متن کاملThe Role of the Glucocorticoids in Developing Resilience to Stress and Addiction
There is emerging evidence that individuals have the capacity to learn to be resilient by developing protective mechanisms that prevent them from the maladaptive effects of stress that can contribute to addiction. The emerging field of the neuroscience of resilience is beginning to uncover the circuits and molecules that protect against stress-related neuropsychiatric diseases, such as addictio...
متن کاملGlucocorticoids-Induced Hypertension: The Prevalence and Risk Factors
Introduction: Despite benefits in the treatment of most autoimmune and inflammatory diseases, glucocorticoids (GCs) have proved side effects including hypertension, diabetes, osteoporosis and lipid disorders. Determining the risk factors for hypertension can facilitate the identification of high-risk individuals and lead to effective control of the side effects. The present study aimed to deter...
متن کاملInhaled glucocorticoids promotes osteoporosis in asthma patients
Background: Recently many studies have focused on the possible role of corticosteroids inhalation on osteoporosis in asthma patients. This study aimed to determine whether the indicatives of bone formation or resorption are different between asthma patients with healthy subjects. Materials and Methods: To achieve this outcome, twenty one middle-aged asthma patients treated with inhaled cortico...
متن کاملGlucocorticoids and the osteoclast.
Glucocorticoid (GC)-induced bone loss is the most common cause of secondary osteoporosis but its pathogenesis is controversial. GCs clearly suppress bone formation in vivo but the means by which they impact osteoblasts is unclear. Because bone remodeling is characterized by tethering of the activities of the two cells, the osteoclast is a potential modulator of the effect of GCs on osteoblasts....
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ژورنال
عنوان ژورنال: Hormones and Behavior
سال: 2019
ISSN: 0018-506X
DOI: 10.1016/j.yhbeh.2018.11.005